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Table 1 Association between the intensity of Rac1, RhoA, Cdc42, Tiam1 and beta-Pix immunoreactivity, and the histological diagnosis

From: Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells

  

Histological diagnosis

  

IR* intensity

without SIL

% (n)

L-SIL

% (n)

p value†

H-SIL

% (n)

p value†

Rac1

     

Low

65 (13)

35.3 (18)

0.02

25.8 (8)

0.005

moderate/high

35 (7)

64.7 (33)

 

74.2 (23)

 

Cdc42

     

Low

60 (12)

58.8 (30)

0.93

38.7 (12)

0.12

moderate/high

40 (8)

41.2 (21)

 

61.3 (19)

 

RhoA

     

Low

60 (12)

49 (25)

0.41

29 (9)

0.03

moderate/high

40 (8)

51(26)

 

71(22)

 

Tiam1

     

Low

80 (16)

19.6 (10)

< 0.001

19.4 (6)

< 0.001

moderate/high

20 (4)

80.4 (41)

 

80.6 (25)

 

Beta-Pix

     

Low

75 (15

62.8 (32)

0.33

35.5 (11)

0.006

moderate/high

25 (5)

37.2 (19)

 

64.5 (20)

 

Total

20

51

 

31

 
  1. *IR = immunoreactivity; † = Chi squared test