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Table 3 Univariate Overall and Disease-Free Survival: Kaplan-Meier medians and log-rank test

From: Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?

  

Overall Survival

Disease-Free Survival

Covariate

 

Median [months] (95% CI)

N

Total N

Log-rank p-value

Median [months] (95% CI)

N

Total N

Log-rank p-value

Overall

 

18 (14, 25)

94

94

 

12 (8, 19)

64

64

 

Age (year)

Young (≤ 65.5)

20 (16, 47)

47

94

0.087

11 (8, 19)

38

64

0.71

 

Old (> 65.5)

15 (9, 24)

47

  

14 (7, 25)

26

  

Size (cm)

Small (≤ 2.0)

25 (9, 47)

20

94

0.60

21 (8, ∞)

12

64

0.17

 

Large (> 2.0)

17 (13, 22)

74

  

11 (7, 17)

52

  

Gender

Female

20 (12, 34)

41

94

0.89

10 (7, 17)

32

64

0.12

 

Male

18 (12, 25)

53

  

19 (9, 46)

32

  

Race

White

17 (13, 26)

66

93

0.65

14 (8, 25)

43

64

0.59

 

NonWhite

22 (8, 26)

27

  

10 (6, 19)

21

  

Grade

1/2

20 (16, 26)

74

93

0.003

14 (10, 19)

52

64

0.031

 

3/4

7 (6, 14)

19

  

6 (2, 25)

12

  

Lymph Nodes

0

26 (22, 48)

27

92

0.009

21 (14, ∞)

20

63

0.008

 

≥ 1

15 (12, 20)

65

  

9 (7, 12)

43

  

Tumor size by

1/2

12 (6, 22)

15

93

0.45

19 (5, ∞)

9

64

0.31

TNM stage

3/4

18 (15, 26)

78

  

11 (8, 19)

55

  

Treatment

Chemo

20 (15, 26)

82

94

<.001

14 (9, 19)

62

64

0.013

 

No chemo

6 (3, ∞)

12

  

5

2

  

RRM1

Low

20 (15, 25)

61

93

0.50

12 (8, 21)

40

63

0.76

IHC Interp.

High

14 (8, 48)

32

  

17 (5, ∞)

23

  

RRM1

Low

24 (16, 26)

39

49

0.21

14 (8, 21)

28

34

0.48

PCR Interp.

High

48 (3, 48)

10

  

17 (11, 17)

6

  

ERCC

Low

20 (12, 25)

41

94

0.83

14 (8, 25)

26

64

0.39

IHC Interp.

High

17 (12, 26)

53

  

12 (7, 19)

38

  

ERCC

Low

16 (12, 25)

46

79

0.39

10 (7, 19)

29

56

0.74

PCR Interp.

High

22 (9, 48)

33

  

14 (6, 21)

27

  
  1. Abbreviations: ∞ = infinity; Interp. = Interpretation