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Figure 5 | BMC Cancer

Figure 5

From: Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation

Figure 5

Ability of agents to suppress VEGF and uPA secretion in UMRC2 cells. UMRC2 cells were pre-treated for 4 h with the indicated doses of agents in reduced serum as in Figure 4. Conditioned medium was collected and both VEGF and uPA levels were analyzed by ELISA. Values were normalized to total protein in conditioned medium and are presented as percent of cytokine secretion relative to control with standard deviation.

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