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Table 3 Clinical outcome according to pEGFR immunohistochemistry

From: Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO)

 

pEGFR detectable

pEGFR non detectable

P value

Overall response rate

(CR and PR)

31%

92%

0.004*

Clinical benefit rate

(CR, PR and SD)

62%

92%

0.160*

Median time to progression

121 days

291 days

0.018**

Median overall survival

285 days

490 days

0.619**

  1. *Fisher's exact test, two-sided
  2. **log-rank P