Breast cancer patients with lobular cancer more commonly have a father than a mother diagnosed with cancer

BMC Cancer

Table 6 Cancer diagnoses in the father related to lobular and ductal breast cancer

	Father with prostate cancer, N = 1676			Father with cancer, not prostate cancer, N = 1597
	OR	95% CI	p-value	OR	95% CI	p-value
Ductal cancer y/n	1.0	0.6-2.0	0.90	0.9	0.7-1.2	0.58
Lobular cancer y/n	2.4	1.1-5.3	0.003	1.8	1.2-2.8	0.006
Other cancers y/n	1.0			1.0
	Father with prostate cancer, age at diagnosis > 60, N = 677			Father with prostate cancer, age at diagnosis < 60, N = 983
	OR	95% CI	p-value	OR	95% CI	p-value
Ductal cancer y/n	1.4	0.5-4.0	0.55	0.9	0.4-2.0	0.74
Lobular cancer y/n	1.9	0.5-7.4	0.34	2.9	1.1-7.8	0.003
Other cancers y/n	1.0			1.0

Logistic regression models with father diagnosed with cancer as the dependent variable. a) Relating prostate cancer in fathers to histopathologic subtype of breast cancer, b) relating father diagnosed cancer, excluding cases with a father diagnosed with prostate cancer, to histopathologic subtype of breast cancer, c) relating breast cancer patients younger than 60 years of age at diagnosis that have a father diagnosed with prostate cancer to histopathologic subtype of breast cancer, and d) relating breast cancer patients diagnosed at age 60 and above With a father diagnosed with prostate cancer to histopathologic subtype of breast cancer. a, b, c, d) were all adjusted for age at diagnosis.

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