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Figure 1 | BMC Cancer

Figure 1

From: Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

Figure 1

Overexpression of Twist induces EMT in Hela and MCF7 cells. (a) Hela and MCF7 cells and their corresponding Twist-overexpressing stable transfectants were analyzed for the expression of N-cadherin, Vimentin, ZO-1, and β-catenin by immunofluorescent staining. Nuclei were visualized with DAPI staining (blue). Cell morphological changes associated with EMT are shown in the phase contrast images. (b) Expression of E-cadherin, Twist, N-cadherin and vimentin in these cells was analyzed by Western blotting. β-tubulin served as a loading control.

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BMC Cancer

ISSN: 1471-2407

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