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Table 5 Specificity and sensitivity values for various intraoperative margin assessment methods

From: High-frequency ultrasound for intraoperative margin assessments in breast conservation surgery: a feasibility study

Method and references

Specificity

Sensitivity

Touch preparation cytology [45, 46]

83-100%

75-96%

Frozen section analysis [5, 47, 48]

92-100%

65-78%

Near-field RF spectroscopy [49]

70%

70%

Raman spectroscopy [50]

93%

83%

Optical coherence tomography [11]

82%

100%

Fluorescence and reflectance spectroscopy [51]

96%

85%

Low-freq. (2-10 MHz) ultrasonic attenuation [27]

90%

80%

  1. Values represent comparison between normal vs. malignant tissue.