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Table 4 Coefficients of the linear risk score for z-score normalized log2-expression values.

From: A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence

Gene

Coefficient

FC (microarray)

FC (RQ-PCR)

p -value (qPCR)

MMP1

0.63

405

798

9E-16

COL4A1

0.25

3.7

4.3

7E-09

P4HA2

0.45

2.7

2.8

1E-06

THBS2

0.34

3

1.9

6E-03

  1. Fold-change (FC) is the geometric-average expression in tumors relative to surgical resection margins. P-values are for tumor/margin differential expression in the qPCR (independent validation set) (Wilcoxon Rank Sum test)
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BMC Cancer

ISSN: 1471-2407

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