Skip to main content

Table 1 Comparison of Presence/Absence of AIA and the Patient Background Factors

From: The time since last menstrual period is important as a clinical predictor for non-steroidal aromatase inhibitor-related arthralgia

Background

w/o AIA(%)

with AIA(%)

P-value

  

n = 214

n = 114

 

Age (yrs)

< 55

22(53.7)

19(46.3)

NS*

 

55-65

97(62.6)

58(37.4)

 
 

65 <

95(72.0)

37(28.0)

 

Age at menarche (yrs)

< 12

7(46.7)

8(53.3)

P = 0.036*

 

15-Dec

183(64.7)

100(35.3)

 
 

15 <

22(84.6)

4(15.4)

 

No. of childbirths

0

27(71.1)

11(28.9)

NS*

 

2-Jan

132(63.5)

76(36.5)

 
 

2 <

53(66.3)

27(33.8)

 

Body mass index (kg/m2)

< 25

150(68.2)

70(31.8)

NS*

 

25-30

64(59.3)

44(40.7)

 

Past history of Arthritis

Yes

48(71.6)

19(28.4)

NS*

 

No

166(63.6)

95(36.4)

 

Time since LMP (yrs)

< 5

39(54.9)

32(45.1)

p < 0.001*

 

10-May

44(53.7)

38(46.3)

 
 

10 <

131(74.9)

44(25.1)

 

Pre-treatment (HT and/or CT)

No

134(68.7)

61(31.3)

NS*

 

Yes

80(60.2)

53(39.8)

 

Pre-treatment (HT)

No

166(64.8)

90(35.2)

NS**

 

Yes

48(66.7)

24(33.3)

 

With pre-treatment: (Chemo with taxane)

No

17(51.5)

16(48.5)

NS*

 

Yes

27(56.3)

21(43.8)

 

Stage

0

17(60.7)

11(39.3)

NS**

 

I

112(62.9)

66(37.1)

 
 

II

80(70.8)

33(29.2)

 
 

III

5(62.5)

3(37.5)

 
 

IV

0

1

 

Metastasis to LNs

Yes

68(63.6)

39(36.4)

NS*

 

No

118(65.9)

61(34.1)

 
 

Nd

28

14

 

ER

+

204(64.4)

113(35.6)

NS**

 

-

10(90.9)

1(9.1)

 
  1. AIA: aromatase inhibitor related arthralgia; LMP: last menstrual period;
  2. HT: hormone therapy; CT: chemotherapy; Nd: not detected; ER: estrogen receptor;
  3. w/o: without;
  4. *:Chi-square test; **:Fisher's exact test.