Figure 2

Oncolytic activity of RSV against androgen-dependent and androgen-independent prostate cancer cells in the absence and presence of androgen. (a) RSV infection of LNCaP cells (in the presence or absence of androgen) were measured by plaque assay as described in Figure. 1a. Standard deviations are shown by the error bars. (b) Morphology of mock-infected or RSV-infected LNCaP cells (in the presence or absence of androgen). (c) Apoptosis of mock-infected (- RSV) and RSV-infected (+ RSV) LNCaP cells (in the presence or absence of androgen). Apoptosis assay was performed as described in Figure 1 d. The figure shows the percentage of cells undergoing apoptosis. Standard deviations are shown by the error bars. (d) RSV infection of C4-2B cells (in the presence or absence of androgen) were measured by plaque assay as described in Figure. 1a. Standard deviations are shown by the error bars. (e) Morphology of mock-infected or RSV-infected C4-2B cells (in the presence or absence of androgen).