A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

BMC Cancer

Table 2 Comparing Groups: End of study tumor summary

	ErbB2	Bigenic	IGF-I	Wild Type
Number of Tumors	19(20) = 95%	19(21) = 90%	0(25)	0(22)
Mean Time to Tumor Formation (MTTF)	224 days 30 wks/7.5 m	233 days 33 wks/8.3 m	NA	NA
Average Number of Tumors per Animal	2.2 (11) = 55%	2.3 (13) = 60%	NA	NA

Number of tumors = animals that got mammary tumors (total number of animals) %- percentage of animals with mammary tumors per group; Average number of tumors per animal = average number of mammary gland tumors per animal (number of animals with multiple tumors), %- percentage of animals with multiple tumors per group. NA = not applicable. ErbB2 = MMTV-ErbB2 transgenic; Bigenic = TTR-IGF-I-ErbB2 bigenic; IGF-I = TTR-IGF-I transgenic; Wild Type = control; wks = weeks; m = months.

ISSN: 1471-2407