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Figure 3 | BMC Cancer

Figure 3

From: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors

Figure 3

BA inhibits luciferase activity in RKO cells transfected with GC-rich constructs. Transfection with constructs containing Sp1 (A), Sp3 (B) and Sp-regulated (C) gene promoter constructs. RKO cells were transfected with the indicated constructs, treated with DMSO or BA, and luciferase activity (normalized to β-galactosidase) was determined as described in the Materials and Methods. Results are expressed as means ± SE for at least 3 replicated determinations as significant (p < 0.05) is indicated (*).

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BMC Cancer

ISSN: 1471-2407

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