Table 6 Differentially expressed miRNAs between patients and healthy individuals: Testing against alternative that a miRNA is downregulated in patients

hsa-miR-32

0.0001

MI0000090

chr 9: intronic (C9orf5)

c.*53C > T

+ (in families 1, 248)

hsa-miR-30a

0.0102

MI0000088

chr 6: intronic (C6orf155)

hsa-miR-33a

0.0184

MI0000091

chr 22: intronic (SREBF2)

hsa-miR-345

0.0210

MI0000825

chr 14: intergenic

hsa-miR-195

0.0245

MI0000489

chr 17: intronic ( AC027763 )

c.*53C > T

+ (in families 292, 362, 408)

hsa-miR-487b

0.0279

MI0003530

chr 14: intergenic

c.*53C > T

+ (in families 248, 292)

hsa-miR-370

0.0292

MI0000778

chr 14: intergenic

hsa-miR-770-5p

0.0305

MI0005118

chr 14: intronic ( MEG3 )

c.3174G > A

-

hsa-miR-29c

0.0330

MI0000735

chr 1: intergenic

c.1327C > G

c.2125C > T

+ (in families 1, 248, 362)

hsa-miR-34c-3p

0.0351

MI0000743

chr 11: intergenic

hsa-miR-148a

0.0426

MI0000253

chr 7: intergenic

hsa-miR-20b

0.0431

MI0001519

chr X: intergenic

+ (in family 1)

hsa-miR-29b

0.0478

29b-1: MI0000105

chr 7: intronic (AC016831)

29b-2: MI0000107

chr 1: intergenic

hsa-miR-212

0.0482

MI0000288

chr 17: intergenic

c.3174G > A

-

hsa-miR-7

0.0490

7-1: MI0000263

chr 9: intronic (HNRNPK)

7-2: MI0000264

chr 15: intergenic

7-3: MI0000265

chr 19: intronic (C19orf30)