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Table 1 Demographics of high-risk breast cancer subjects

From: Association of Rad51 polymorphism with DNA repair in BRCA1 mutation carriers and sporadic breast cancer risk

 

Unaffected

Affected

p-value

 

N = 56

N = 82

 

Age at Diagnosis Range (yrs)

25-78

27-79

 

Mean Age at Diagnosis (yrs)

47.44

44.73

0.19*

Median Age at Diagnosis (yrs)

50

45

 

Standard Deviation

13.63

10.65

 

Mutation

   

185delAG (BRCA1)

19 (31.6%)

21 (24.7%)

 

5382insC

4 (7.0%)

12 (14.8%)

0.15**

Other

35 (61.4%)

49 (60.5%)

0.57**

 

Relationship Information

  
  

Num. Pairs

 

Sister-Sister

 

15

 

Other relationship

   

i.e. Aunt-Niece and Cousins

 

16

 
  1. *Unpaired t-test, t = 1.13, df = 136
  2. **Determined by Fisher's exact test.