Increased incidence of myelodysplastic syndrome and acute myeloid leukemia following breast cancer treatment with radiation alone or combined with chemotherapy: a registry cohort analysis 1990-2005

Table 5 Expected and observed incidence rates of MDS/AML by age per 100000 person years.

Leukemia Type	Age	Expected Rate*	Person years	Observed Rate	Expected Cases	Observed Cases	Rate Ratio (95% CI)
MDS	< 65	1.6	28538	17.5	0.46	5	10.88 (3.84, 24.03)
	≥ 65	31.6	12027	41.6	3.80	5	1.31 (0.47, 2.84)
	All	6.7	40565	24.7	2.71	10	3.70 (1.85, 6.54)
AML	< 65	2.0	28538	10.5	0.57	3	5.32 (1.31, 14.04)
	≥ 65	14.0	12027	33.3	1.68	4	2.38 (0.73, 5.61)
	All	4.0	40565	17.3	1.62	7	4.32 (1.85, 8.45)
MDS/AML	< 65	3.6	28538	28.1	1.03	8	7.82 (3.54, 14.77)
	≥ 65	45.6	12027	74.8	5.48	9	1.64 (0.79, 2.98)
	All	10.6	40565	41.9	4.30	17	3.94 (2.34, 6.15)

ISSN: 1471-2407