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Table 2 14 selected differential expression genes.

From: Clinical relevance of DNA microarray analyses using archival formalin-fixed paraffin-embedded breast cancer specimens

Gene Symbol

The 25 breast cancers

NKI-295 dataset

GIS-251 dataset

 

FNAB array

FFPE array

FFPE qPCR

FFPE vs. FNAB

FFPE vs. qPCR

Array

OS

DMFS

Array

OS

RFS

 

P1

P1

P1

r2

r3

P1

P4

P4

P1

P4

P4

AKR7A3

0.001

0.000

0.000

0.701

0.653

0.000

0.000

0.248

0.000

0.284

0.787

ANKRA2

0.001

0.009

0.021

0.522

0.390

0.000

0.021

0.071

0.000

0.064

0.139

ANLN

0.000

0.002

0.007

0.731

0.543

0.000

0.002

0.010

0.000

0.009

0.004

CA12

0.000

0.000

0.000

0.607

0.710

0.000

0.010

0.299

0.000

0.358

0.468

DNALI1

0.000

0.000

0.000

0.681

0.646

0.000

0.009

0.097

0.000

0.565

0.582

ERBB2

0.000

0.008

0.000

0.370

0.815

0.000

0.005

0.024

0.000

0.006

0.001

ESR1

0.000

0.000

0.000

0.787

0.862

0.000

0.004

0.030

0.000

0.698

0.742

FUT3

0.001

0.001

0.003

0.542

0.444

0.000

0.061

0.009

0.000

0.023

0.287

GREB1

0.001

0.001

0.000

0.732

0.711

0.000

0.054

0.667

0.000

0.023

0.487

KIAA1407

0.000

0.000

0.010

0.460

0.337

0.000

< 0.001

0.000

0.000

0.006

0.197

KIF2C

0.000

0.001

0.020

0.710

0.647

0.000

< 0.001

0.000

0.000

0.022

0.004

LONRF2

0.001

0.007

0.004

0.398

0.588

0.000

0.001

0.168

0.000

0.294

0.393

MAPT

0.000

0.000

0.000

0.740

0.677

0.000

0.007

0.023

0.000

0.001

0.014

PGR

0.000

0.000

0.000

0.870

0.674

0.000

< 0.001

< 0.001

0.000

0.022

0.206

  1. FNAB, fine needle aspiration biopsy; FFPE, formalin-fixed, paraffin-embedded tissue; qPCR, Quantitative RT-PCR; OS, Overall survival; DMFS, Distant metastasis free survival; RFS, Relapse free survival; 1 P-value of ANOVA test among the 4 ER/Her2 groups; 2Correlation coefficient, Pearson correlation test between FFPE array and FNA array (value in boldface type is statistically significant, P < 0.05); 3Correlation coefficient, Pearson correlation test between FFPE array and FFPE qPCR (value in boldface type is statistically significant, P < 0.05); 4 P-value of Log-rank Test.