Figure 3

Whole-genome view of copy number profile in 81BPG primary culture at first (p1), second (p2) and third (p3) confluences, and in corresponding tumor tissue, using CNAG v3.0 software. Analysis was performed using CNAG v3.0 software, comparing primary culture at each passage and parental tumor tissue to the autologous blood sample. Chromosomes are represented horizontally, from 1 to 22 in different colors, separated by vertical bars. For each sample, the three tracks represent (on log scale): a) "copy number plot": copy number log ratio values of single SNPs; b) "copy number average": copy number log ratio values locally averaged on 10 contiguous SNPs; c) "allele-based analysis": copy number log ratio values for each allele (red and green lines).