Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel

Table 1 The Cell Cycle Analysis of MDA-MB-231 Cells

MDA-MB-231	G0/G1 (%)	S (%)	G2/M (%)
Control	52.70 ± 0.52	43.35 ± 0.95	4.05 ± 0.43
DMSO	55.23 ± 1.17	39.69 ± 2.04	5.09 ± 2.31
TSA	59.25 ± 0.64	35.45 ± 0.38	5.30 ± 0.34*
DAC	46.91 ± 0.16	43.11 ± 0.19	9.98 ± 0.29***
DAC+TSA	46.42 ± 0.81	27.30 ± 1.59	25.29 ± 2.65**
Paclitaxel	42.85 ± 6.51	45.13 ± 5.21	12.01 ± 3.43*
DAC+TSA+Paclitaxel	39.67 ± 2.12	14.6 8 ± 1.87	45.99 ± 0.32***

*P < 0.05, **P < 0.01, ***P < 0.001 compared to control. The data were obtained from three independent experiments and are presented as the mean ± SD.

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