Figure 1
From: MMP28 (epilysin) as a novel promoter of invasion and metastasis in gastric cancer
MMP28 expression correlates with the invasive ability of gastric carcinoma cell lines. (A) PAMC82 sub-lines with low and high invasive abilities were established and tested using the transwell invasion assay. P1-P3 cells indicated increased invasive ability, with no difference observed between P2 and P3 cells. (B) qRT-PCR analysis of MMP28 in PAMC82, P1 and P3 cells indicating MMP28 expression correlates with invasive ability. (C) MMP28 expression correlates with invasive ability in a range of gastric carcinoma cell lines. Top: transwell invasion assays of nine gastric cancer cell lines. Bottom: Western blot analysis of activated and total MMP28.