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Figure 7 | BMC Cancer

Figure 7

From: Down-regulation of NKD1 increases the invasive potential of non-small-cell lung cancer and correlates with a poor prognosis

Figure 7

NKD1 knockdown could enhance the transcriptional activity of MMP-7 gene, and these could be ablated by anti-Dishevelled-1 antibody. Levels of the MMP-7 gene were gradually increased along with increasing doses of NKD1 siRNA in LTEP (A) and LK (B) cells (P < 0.05). However, when DVL-1 specific antibody incubated with NKD1 siRNA in LTEP (A) and LK (B) lines, MMP-7 mRNA level was decreased significantly (P < 0.05).

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