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Table 6 The comparisons of EORTC QLQ-C30 and H&N35 scales for head and neck cancer survivors by different RT techniques

From: Health-related Quality of life in 640 head and neck cancer survivors after radiotherapy using EORTC QLQ-C30 and QLQ-H&N35 questionnaires

 

2DRT

(n = 371)

3DCRT

(n = 127)

IMRT

(n = 142)

 
 

Mean (SD)

Mean (SD)

Mean (SD)

p

EORTC QLQ-C30

    

   Global quality of life

51.7 (19.9)

56.2 (18.6)

60.7 (19.7)b,

<0.01

   Physical functioning

83.1 (17.7)

86.2 (14.1)

86.7 (14.6)b

0.039

   Role functioning

85.6 (22.2)

86.7 (19.4)

88.1 (19.1)

NS

   Emotional functioning

76.6 (20.8)

79.8 (18.0)

79.6 (19.8)

NS

   Cognitive functioning

77.2 (20.7)

79.9 (16.6)

80.0 (20.1)

NS

   Social functioning

73.4 (26.0)

76.7 (20.3)

78.1 (22.0)

NS

   Fatigue

31.0 (21.1)

26.9 (16.8)

26.5 (21.0)

NS

   Nausea/Vomiting

10.3 (19.2)

7.7 (13.6)

8.2 (15.5)

NS

   Pain

23.9 (24.1)

18.5 (16.9)

19.7 (21.7)

NS

   Dyspnea

16.2 (23.4)

15.8 (18.8)

12.1 (18.7)

NS

   Insomnia

26.9 (27.5)

25.6 (22.1)

25.4 (25.0)

NS

   Appetite loss

21.7 (26.7)

18.8 (20.9)

16.4 (21.2)

NS

   Constipation

19.8 (25.2)

19.2 (22.5)

17.1 (20.4)

NS

   Diarrhea

14.8 (21.3)

12.4 (17.8)

13.3 (17.6)

NS

   Financial problems

27.1 (28.1)

23.1 (24.1)

27.6 (26.7)

NS

EORTC QLQ-HN35

    

   Pain

20.8 (22.6)

18.4 (16.7)

15.2 (17.7)

NS

   Swallowing

33.3 (25.6)

28.0 (22.4)

23.9 (21.5)b

<0.01

   Senses (taste/smell)

29.4 (29.0)

26.3 (28.1)

20.6 (22.7)b

<0.01

   Speech

29.6 (26.4)

29.5 (25.7)

22.4 (24.0)b

0.013

   Social eating

31.0 (27.5)

28.5 (27.0)

21.9 (24.3)b

<0.01

   Social contact

21.0 (24.1)

22.7 (24.7)

16.6 (20.3)b

<0.01

   Sexuality

27.4 (28.9)

27.0 (28.0)

21.5 (23.8)

NS

   Teeth

43.2 (30.6)

34.7 (29.1)a

31.2 (26.0)b

<0.01

   Opening mouth

36.5 (31.7)

30.2 (30.4)

25.4 (31.1)b

<0.01

   Dry mouth

54.0 (31.9)

43.8 (28.2)a

41.0 (27.9)b

<0.01

   Sticky saliva

45.1 (32.3)

35.8 (26.1)a

33.6 (27.9)b

<0.01

   Coughing

31.0 (26.9)

29.5 (24.2)

24.5 (21.7)

NS

   Feeling ill

32.3 (26.3)

26.3 (23.0)

24.0 (23.2)b

<0.01

  1. Abbreviations: RT = radiotherapy; 2DRT = two dimensional RT; 3DCRT = three dimensional conformal RT; IMRT = intensity-modulated RT; a: p < 0.05, 3DCRT compared with 2DRT; b: p < 0.05, IMRT compared with 2DRT