| BRAF mutant | BRAF wildtype |  |
K-RAS mutant | 3.4 (1) | 25.5 (40) | Â |
K-RAS wildtype | 96.6 (28) | 74.5 (117) | p = 0.009 |
 | BRAF mutant | BRAF wildtype |  |
PTEN mutant | 13.8 (4) | 0.0 (0) | (FET) |
PTEN wildtype | 86.2 (25) | 100.0 (157) | p < 0.001 |
 | BRAF mutant | BRAF wildtype |  |
PTEN expression negative | 37.0 (10) | 34.5 (50) | Â |
PTEN expression positive | 63.0 (17) | 65.5 (95) | p = 0.80 |
 | BRAF mutant | BRAF wildtype |  |
PIK3CA mutant | 13.8 (4) | 5.7 (9) | (FET) |
PIK3CA wildtype | 86.2 (25) | 94.3 (148) | p = 0.12 |
 | K-RAS mutant | K-RAS wildtype |  |
PIK3CA mutant | 7.3 (3) | 6.9 (10) | (FET) |
PIK3CA wildtype | 92.7 (38) | 93.1 (135) | p = 1.00 |
 | K-RAS mutant | K-RAS wildtype |  |
PTEN mutant | 0.0 (0) | 2.8 (4) | (FET) |
PTEN wildtype | 100.0 (41) | 97.2 (141) | p = 0.58 |
 | K-RAS mutant | K-RAS wildtype |  |
PTEN expression negative | 41.7 (15) | 33.1 (45) | Â |
PTEN expression positive | 58.3 (21) | 66.9 (91) | p = 0.34 |
 | PIK3CA mutant | PIK3CA wildtype |  |
PTEN expression negative | 23.1 (3) | 35.8 (57) | (FET) |
PTEN expression positive | 76.9 (10) | 64.2 (102) | p = 0.55 |
 | PIK3CA mutant | PIK3CA wildtype |  |
PTEN mutant | 7.7 (1) | 1.7 (3) | (FET) |
PTEN wildtype | 92.3 (12) | 98.3 (170) | p = 0.25 |