Figure 3From: Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells Effect of huMETCAM/MUC18 expression on in vitro motility of MCF7 cells (6 hours). The motility of the pooled 2D and 3D clones of MCF7 was determined 6 hours after seeding the cells as described in "Materials and Methods" by using a pore size of 8 μm. 7.5 to 15 μg/ml of the anti-huMCAM/MUC18 antibody (open columns) or the isotype control antibody (chicken IgY) (filled columns) was added to block the motility of these clones. Means and standard deviations of triplicate values of the test are shown.Back to article page