Figure 3

EGFR expression congruency. A: Comparison of the intensity of positive staining of EGFR obtained by immunohistochemistry and gene expression measured by Affymetrix gene chips: Gene expression values are congruent with EGFR detection on the protein level. The upper bar shows the EGFR expression on protein level (pink = no protein expression, green = incomplete membranous stain and yellow = complete membranous stain). The expression values of elements representing EGFR gene expression (middle) are indicated by color code shown in the lowest bar (blue = low gene expression and red = high gene expression). In B the results of the Spearmans Rank Order Correlation of the gene expression values obtained by microarray analyses and EGFR protein levels measured by IHC are shown.