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Table 1 Amplification efficiency

From: Translating tumor biology into personalized treatment planning: analytical performance characteristics of the Oncotype DX®Colon Cancer Assay

Gene

Amplification Efficiency (%)

Lower 95% Confidence Interval

Upper 95% Confidence Interval

ATP5E

96.3

94.4

98.3

BGN

97.7

95.8

99.6

MYC

97.3

95.1

99.6

FAP

103.3

100.0

106.8

GADD45B

106.9

101.7

112.5

GPX1

97.8

95.5

100.2

INHBA

102.9

100.3

105.6

MK167

100.8

97.4

104.5

MYBL2

99.9

97.0

103.0

PGK1

97.0

95.3

98.7

UBB

98.0

95.4

100.6

VDAC2.1

97.1

95.3

98.9

  1. Amplification efficiencies and 95% confidence intervals for the 12 genes. Amplification efficiencies range from 100% ± 7%, and vary due to additive assay error from the 17-point dilution series, PCR inhibition, or primer-dimer formation which can result in amplification efficiency greater than 100%.