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Figure 3 | BMC Cancer

Figure 3

From: Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progressioan

Figure 3

Phenotypic presentation of PC3-AKR1C3 transfectants from literature analysis. Relationships between differentially expressed genes in PC3-AKR1C3 transfectants and the most significantly overrepresented keywords published with those genes in MEDLINE abstracts and titles are identified. Genes are circled, keywords are not circled. Thickness of the line correlates with the mutual information between the terms (thicker lines mean more mutual information). (A) Up-regulated genes that have been documented as related to aggressive carcinomas, PSA, β-catenin, and ER. (B) Down-regulated genes that are related to angiogenesis, tumor suppression and, more specifically, tumor suppression via p53.

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BMC Cancer

ISSN: 1471-2407

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