Figure 1From: Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells 5-FU induced cytotoxicity in HCT-116 p53+/+ and HCT-116 p53-/- cell lines in a dose-dependent manner at 48 h ( p < 0.001).Back to article page