cycle phase | control | SI 34 1 μM | SI 34 10 μM | Etoposide 50 μM |
---|---|---|---|---|
24 hours treatment | ||||
Sub G0 | 0 | 0 | 0 | 20 ± 1.2 *** |
G0/G1 | 72 ± 1.7 | 81 ± 2.6 | 83 ± 1.8 * | 69 ± 1.4 |
S | 9 ± 0.5 | 4 ± 0.3 * | 3 ± 0.7 * | 3 ± 0.2 * |
G2/M | 19 ± 0.7 | 15 ± 1.0 | 14 ± 0.9 |  8 ± 0.8 * |
48 hours treatment | ||||
Sub G0 | 0 | 12 ± 1.1 * | 24 ± 2.2 *** | 44 ± 2.7 *** |
G0/G1 | 74 ± 3.1 | 76 ± 3.5 | 70 ± 3.6 | 48 ± 2.6 * |
S | 8 ± 0.8 | 4 ± 0.5 * | 2 ± 0.1 * | 1 ± 0.1 ** |
G2/M | 18 ± 1.1 | 8 ± 1.1 * | 4 ± 0.1 ** | 7 ± 0.3 * |
72 hours treatment | ||||
Sub G0 | 0 | 42 ± 3.2 *** | 45 ± 2.9 *** | 80 ± 4.1 *** |
G0/G1 | 73 ± 4.7 | 58 ± 3.2 * | 55 ± 2.97 * | 20 ± 1.4 *** |
S | 11 ± 1.0 | 0 *** | 0 *** | 0 *** |
G2/M | 16 ± 0.8 | 0 *** | 0 *** | 0 *** |