Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients

Table 1 Clinicopathological characteristics of 17 patients.

Patient and tumor characteristics	Number of cases
Age	Mean age 68.7 ± 9.3
Gender	13 males, 4 females
Type of analyzed tissue *
Normal	17
Normal near Tumor	9
Adenoma	18**
Tumor	17*** (1 with G1, 6 with G2; 8 with G3; 1 with G4)

* Four different types of tissues were examined for expression of DEFA 1-3, DEFA 6 and β- actin genes.
** One donor has two types of adenoma
*** For 1 out of 17 analyzed donors the clinical description about the grade of the tumor was not available. In addition, 1 out of the total 17 donors investigated does not possess tumor tissue.

ISSN: 1471-2407