Skip to main content
Figure 2 | BMC Cancer

Figure 2

From: LATS2 is De-methylated and Overexpressed in Nasopharyngeal Carcinoma and Predicts Poor Prognosis

Figure 2

Kaplan-Meier survival curves of NPC patients. A, The five-year overall survival rate of 220 NPC patients was 66.18%. B, The five-year overall survival rates were 73.96% and 57.23%, in NPC patients whose tumors showed low levels of LATS2 expression (n = 109) and high levels of LATS2 expression (n = 111), respectively; there was a significant difference in the overall survival rate between the two groups (P = 0.006). C, No significant differences in five-year survival rates were found between low levels of LATS2 expression (n = 29) and high levels of LATS2 expression (n = 25) in NPC patients with early stage disease (stage I - II, P = 0.099). D, The five-year overall survival rates were 70.57% and 57.59% in patients with late stage disease (stage III - IV) whose tumors showed low levels of LATS2 expression (n = 80) and high levels of LATS2 expression (n = 86), respectively; there was a significant difference in the overall survival rate between the two groups (P = 0.032). E, No differences were found in overall survival between low levels of LATS2 expression (n = 28) and high levels of LATS2 expression (n = 30) in NPC patients with differentiated non-keratinising carcinoma (WHO type II, P = 0.125). F, The five-year overall survival rates were 70.91% and 62.23% in patients with undifferentiated carcinoma (WHO type III) whose tumors showed low levels of LATS2 expression (n = 81) and high levels of LATS2 expression (n = 81), respectively; there was a significant difference in the overall survival rate between the two groups (P = 0.040).

Back to article page