Core needle biopsy specimens | ||||
---|---|---|---|---|
 | Number of tumors (%) | |||
 | Total | HER2 gene amplification by FISH | ||
 |  | Positive | Equivocal* | Negative |
HER2 IHC score | ||||
3+ | 21 | 20 (95) | 0 (0) | 1 (5) |
2+ | 19 | 11 (58) | 0 (0) | 8 (42) |
0 or 1+ | 60 | 2 (3) | 0 (0) | 58 (97) |
Total | 100 | 33 (33) | 0 (0) | 67 (67) |
Surgically resected specimens | ||||
 | Number of tumors (%) | |||
 | Total | HER2 gene amplification by FISH | ||
 |  | Positive | Equivocal* | Negative |
HER2 IHC score | ||||
3+ | 10 | 10(100) | 0 (0) | 0 (0) |
2+ | 7 | 3 (43) | 0 (0) | 4 (57) |
0 or 1+ | 8 | 0 (0) | 0 (0) | 8 (100) |
Total | 25 | 13 (52) | 0 (0) | 12 (48) |