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Table 3 Treatment and toxicity

From: Esophageal cancer in the elderly: an analysis of the factors associated with treatment decisions and outcomes

 

All patients (n = 282)

Patients without visceral metastasis (n = 220)

Patients with visceral metastasis (n = 62)

  

Curative treatment (n = 151)

BSC

(n = 69)

Palliative treatment (n = 30)

BSC

(n = 32)

Dysphagia palliative treatment

     

naso-gastric tubes

15 (5.3%)

7 (4.6%)

4 (5.8%) *

3 (10.0%)

1 (3.1%) **

gastrostomy

11 (3.9%)

4 (2.6%)

6 (8.7%)

0

1 (3.1%)

endoscopic dilation

44 (15.6%)

19 (12.6%)

14 (20.3%)

5 (16.7%)

5 (3.1%)

oesophageal stent

63 (22.3%)

3 (2.0%)

37 (53.6%)

5 (16.7%)

18 (3.1%)

Initial cancer treatment

     

Mucosectomy

6 (2.1%)

6 (4.0%)

-

-

-

PDT

18 (6.4%)

14 (9.3%)

3 (4.3%)

1 (3.3%)

-

Surgery

13 (4.6%)

13 (8.6%)

-

-

-

Chemoradiotherapy

119 (42.2%)

111 (73.5%)

-

-

-

Radiotherapy

8 (2.8%)

7 (4.6%)

-

-

-

Chemotherapy

22 (7.8%)

-

2 (2.9%)

20 (66.7%)

-

Severe adverse effects

48 (17.0%)

31 (20.5%)

4 (5.8%) *

10 (33.3%)

3 (9.4%) **

Dysphagia evolution

     

Regression at 2 months (n = 229)

139 (60.7%)

87 (64.0%)

25 (52.12%)

16 (55.2%)

11 (68.7%)

Recurrence (n = 103)

60 (58.2%)

35 (67.3%)

15 (68.2%)

7 (36.8%)

3 (30%)

  1. n: number of patients, BSC: best supportive care, *: p < 0.05 curative treatment vs BSC,
  2. **: p < 0.05 palliative treatment vs BSC, PDT: Phototherapy dynamic,
  3. : Many patients were not evaluable because they had died within 2 months