Co-expression of nuclear and cytoplasmic HMGB1 is inversely associated with infiltration of CD45RO+ T cells and prognosis in patients with stage IIIB colon cancer

Table 3 Relationship between the expression of HMGB1 and the density of TILs as well as patient characteristics (N = 72)

Characteristic	HMGB1 expression (-)- (+) (++)-(+++)		P
Gender			0.058
Male	22	18
Female	10	22
Age, years			0.113
≥60	14	25
<60	18	15
Tumor sites			0.476
Left hemicolon	19	27
Right hemicolon	13	13
Pathological grade			0.182
G1	4	6
G2	22	32
G3	6	2
Density of CD3+cells (cells per high-power field)			0.013
≥16
<16	20	35	0.006
Density of CD45RO+cells (cells per high-power field)	12	5
≥24	19	35
<24	13	5

ISSN: 1471-2407