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Table 3 Distribution of DNA damage and percent residual DNA damage among cases and current smoker controls

From: Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers

Tail Extent Moment

Mean ± SE

Cases

Controls

P-value

Adjusted

OR

95% CL

 

Current

Smokers

Current

Smokers

   

H2O2 + OGG1

44.6 ± 0.89

18.4 ± 1.37

<0.001

  

Percent Residual Damage (PRD)

237.4 ± 8.7

180.8 ± 50.7

<0.001

  

Residual Damage Logistic Regression (RDLR)

≤75th N (%)

13(43.3)

41(75.9

   

>75th N (%)

17(56.7)

13(24.1)

   
 

5.07

1.80-14.24

   
  

Referent

 

5.07

1.80-14.24

  1. P-value from t-test; TEM RDLR dichotomized by 75th percentile of the controls. Adjusted by age, sex and family history of a smoking-related cancer