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Table 2 Multivariate hazards of breast cancer-specific and all cause mortality at 30 years for 322 patients undergoing adjuvant radiotherapy and chemotherapy with primary operable breast cancer, stratified by oestrogen receptor status.

From: Adjuvant radiotherapy and chemotherapy in breast cancer: 30 year follow-up of survival

  

Cancer-specific

survival

Overall

survival

 

Patients

(n = 322)

Hazard ratio

(95% CI)

P-value

Hazard ratio

(95% CI)

P-value

Age (>50 years)

 

1.34 (0.95-1.89)

0.097

1.63 (1.19-2.22)

0.002

Deprivation (DEPCAT)

  

0.226

 

0.322

1-2

 

1.00

 

1.00

 

3-5

 

1.04 (0.68-1.60)

0.845

0.94 (0.65-1.36)

0.740

6-7

 

1.39 (0.90-2.14)

0.144

1.21 (0.82-1.77)

0.332

Involved lymph nodes

     

1,2 or 3

 

1.00

 

1.00

 

≥4

 

1.88 (1.34-2.63)

<0.001

1.59 (1.17-2.14)

0.003

Treatment

  

0.220

 

0.309

Radiotherapy

 

1.24 (0.81-1.90)

0.324

1.02 (0.70-1.48)

0.921

Radiotherapy + CMF

 

1.00

1.00

1.00

 

CMF

 

1.43 (0.96-2.13)

0.082

1.28 (0.90-1.81)

0.169

  1. CMF, cyclophosphamide, methotrexate and 5-fluorouracil.