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Table 2 Haplotype Analysis of TLR9 rs187084 (T > C) and rs5743836 (T > C) and endometrial cancer risk

From: Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk

Gene

Haplotype

Cases n (%)

Controls n (%)

OR (95% CI)

p value

TLR9 (rs187084 and rs5743836)

TT

98 (51.3)

141 (48.5)

1.00 (reference)

 
 

CT

65 (34.0)

90 (30.9)

1.09 (0.75-1.57)adj^

p = 0.66

    

0.99 (0.75-1.31)

p = 0.94

 

TC

26 (13.6)

39 (13.4)

1.07 (0.63-1.80)adj^

p = 0.76

    

0.92 (0.63-1.36)

p = 0.68

 

CC

2 (1.1)

21 (7.2)

0.10 (0.02-0.46) adj^

p = 0.003

    

0.11 (0.03-0.44)

p = 0.002

  1. NB: Variant allele is underlined.
  2. ^ Odds Ratio adjusted for age, BMI, diabetes, HBP, history of cancer, HT, smoking and alcohol use.