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Table 2 Methylation positive rates of 6 tumor suppressor genes in primary cancer tissues and lymph nodes metastasis

From: Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers

Genes

Number of methylated cases (positive rate %)

 

Primary cancer

Lymph nodes metastasis

pvalue*

HIN-1

28 (73.7)

26 (68.4)

0.508

CDH13

32 (84.2)

34 (89.5)

0.688

RIL

25 (65.8)

25 (65.8)

1.000

RASSF1A

25 (65.8)

24 (63.2)

1.000

RARβ2

23 (60.5)

21 (55.3)

0.774

E-cadherin

7 (18.4)

9 (23.7)

0.754

  1. *Binomial exact test for paired comparison.