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Figure 2 | BMC Cancer

Figure 2

From: Expression profile and specific network features of the apoptotic machinery explain relapse of acute myeloid leukemia after chemotherapy

Figure 2

Correlation among network centrality, expression and involvement in drug response . yFiles Circular Layout of the AM network that emphasizes the nodes with high closeness and high involvement in drug response. The nodes with high overall drug response (number of literature citations for drugs) are localized on the left half of the circle (attribute circle layout, based on number of literature citations for drugs). The size of the nodes is related to network closeness. The colours indicate the expression fold change of AM genes (chemoresistant vs chemosensitive), according to the bar shown below the network. The node line width indicates the number of literature citations for drugs. As shown by red arrows, all nodes with altered expression are characterized by high closeness and involvement in drug response.

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BMC Cancer

ISSN: 1471-2407

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