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Table 1 Gene Identifications, Categories and Score affiliations

From: Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue

Gene

Category

Accession Nr.

Description

AS

Score

GUSB

Control

NM_000181.1

glucuronidase, beta

81

control

RPLP0

Control

NM_053275.3

NM_001002.3

ribosomal protein, large, P0

105

control

UBB

Control

NM_018955.2

ubiquitin B

120

control

AR

ER

NM_001011645.1

NM_000044.2

androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)

72

ER_8

ERBB4

ER

NM_001042599.1

NM_005235.2

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

77

ER_8

ESR1

ER

NM_000125.2

estrogen receptor 1

62

ER_8

ER_4

FOXA1

ER

NM_004496.2

forkhead box A1

74

ER_8

GATA3

ER

NM_001002295.1

NM_002051.2

GATA binding protein 3

80

ER_8

MAPT

ER

NM_016834.2

NM_016835.2

NM_016841.2

NM_005910.3

microtubule-associated protein tau

60

ER_8

MYB

ER

NM_005375.2

v-myb myeloblastosis viral oncogene homolog (avian)

96

ER_8

XBP1

ER

NM_005080.2

X-box binding protein 1

60

ER_8

BCL2

ER

NM_000633.2

B-cell CLL/lymphoma 2

81

ER_4

GREB1

PGR

NM_033090.1

NM_148903.1

NM_014668.2

GREB1 protein

77

PGR_5

PGR

PGR

NM_000926.3

progesterone receptor

118

PGR_5 ER_4

RAB31

PGR

NM_006868.2

RAB31, member RAS oncogene family

109

PGR_5

RBBP8

PGR

NM_203291.1

NM_203292.1

NM_002894.2

retinoblastoma binding protein 8

75

PGR_5

SERPINA3

PGR

NM_001085.4

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

70

PGR_5

SCUBE2

PGR

NM_020974.1

CEGP1, signal peptide, CUB domain, EGF-like 2

64

ER_4

ERBB2

HER2

NM_001005862.1

NM_004448.2

v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

120

HER2_2

GRB7

HER2

NM_005310.2

growth factor receptor-bound protein 7

70

HER2_2

CCNB2

Proliferation

NM_004701.2

cyclin B2

73

PRO_10

CCNE2

Proliferation

NM_057735.1

NM_057749.1

cyclin E2

70

PRO_10

CDC2

Proliferation

NM_033379.2 NM_001786.2

cell division cycle 2, G1 to S and G2 to M

92

PRO_10

CENPF

Proliferation

NM_016343.3

centromere protein F, 350/400 ka (mitosin)

99

PRO_10

KIF20A

Proliferation

NM_005733.1

kinesin family member 20A

130

PRO_10

MKI67

Proliferation

NM_002417.3

antigen identified by monoclonal antibody Ki-67

131

PRO_10 PRO_5

ORC6L

Proliferation

NM_014321.2

origin recognition complex, subunit 6 like (yeast)

78

PRO_10

PRC1

Proliferation

NM_199413.1

NM_199414.1

NM_003981.2

protein regulator of cytokinesis 1

66

PRO_10

SPAG5

Proliferation

NM_006461.3

sperm associated antigen 5

114

PRO_10

TOP2A

Proliferation

NM_001067.2

topoisomerase (DNA) II alpha 170 kDa

125

PRO_10

AURKA

Proliferation

NM_003600.2

STK15 aurora kinase A

85

PRO_5

BIRC5

Proliferation

NM_001012271.1

NM_001168.2

baculoviral IAP repeat-containing 5 (survivin)

93

PRO_5

CCNB1

Proliferation

NM_031966.2

cyclin B1

104

PRO_5

MYBL2

Proliferation

NM_002466.2

v-myb myeloblastosis viral oncogene homolog (avian)-like 2

81

PRO_5

  1. Abbreviation: AS, amplicon size