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Table 6 Age and habits distribution in relation to alleles in HNSCC and Controls

From: Synergistic effect of stromelysin-1 (matrix metalloproteinase-3) promoter (-1171 5A->6A) polymorphism in oral submucous fibrosis and head and neck lesions

Characteristics

HNSCC

(N = 135)

Control

(N = 126)

 

6A/6A

5A/6A

5A/5A

p-value

5A/5A

6A/6A

5A/6A

(p-value)

Age (Yrs)

        

Mean ± SD

42 ± 16.5

47 ± 10.8

41 ± 9.86

0.42

17.5 ± 0.7

36.7 ± 12.4

38.8 ± 16

0.41

Tobacco with Areca nut

        

Chewer

98(92.45%)

16(69.56%)

4 (66.6%)

 

2(100%)

71(64.5%)

12(85.7%)

0.12

Non Chewer

8(7.54%)

7(30.43%)

2 (33.3%)

0.003

0

39(35.5%)

2(14.3%)

 

Smoking status

        

Smoker

88(83.01%)

15(65.21%)

4 (66.6%)

 

0

47(42.7%)

4(28.6%)

0.11

Non-smoker

18(16.98%)

8(34.78%)

2 (33.3%)

0.037

2(100%)

63(57.3%)

10(71.4%)

 

Alcohol Intake

        

Drinker

72(67.92%)

14(60.86%)

3 (50%)

0..81

0

25(22.7%)

1(7.1%)

0.24

Non Drinker

34(32.07%)

9(39.1%)

3 (50%)

 

2(100%)

85(77.3%)

13(92.9%)

 
  1. [Data was expressed as mean ± SD and %. Fischer exact test is used for habits in HNSCC cases and control groups]
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BMC Cancer

ISSN: 1471-2407

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