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Table 4 Correlation between HIF-1α, GLUT-1 and other studied biomarkers in lymph node metastases in patients without and after preoperative chemotherapy.

From: Relationships between hypoxia markers and the leptin system, estrogen receptors in human primary and metastatic breast cancer: effects of preoperative chemotherapy

Compared biomarkers

Lymph node metastases without preoperative chemotherapy; n = 35

Lymph node metastases after preoperative chemotherapy; n = 30

 

P

r

p

r

HIF-1α - Ob

0.013

0.533

0.465

0.168

HIF-1α - ObR

0.083

0.387

0.150

0.302

HIF-1α - ERα

0.133

-0.327

0.908

0.024

HIF-1α - ERβ

0.119

0.474

0.188

0.272

HIF-1α - Ki-67

0.604

-0.167

0.951

-0.013

HIF-1α -GLUT-1

0.776

-0.177

0.401

-0.198

GLUT-1 - Ob

0.405

0.242

0.361

-0.209

GLUT-1 - ObR

0.261

-0.309

0.335

-0.216

GLUT-1 - ERα

0.017

-0.606

0.021

-0.469

GLUT-1 - ERβ

0.677

-0.117

0.785

0.059

GLUT-1 - Ki-67

0.078

0.468

0.749

0.069

  1. n - number of studied cases.