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Table 3 Correlation between HIF-1α, GLUT-1 and other studied biomarkers in primary breast cancer in patients without and after preoperative chemotherapy.

From: Relationships between hypoxia markers and the leptin system, estrogen receptors in human primary and metastatic breast cancer: effects of preoperative chemotherapy

Compared biomarkers

Primary tumors without preoperative chemotherapy; n = 71

Primary tumors after preoperative chemotherapy; n = 45

 

p

r

P

r

HIF-1α - Ob

<0.0001

0.532

0.116

0.288

HIF-1α - ObR

0.002

0.319

0.007

0.445

HIF-1α - ERα

0.055

-0.194

0.244

0.191

HIF-1α - ERβ

0.002

0.408

0.031

0.346

HIF-1α - Ki-67

0.822

-0.031

0.801

0.042

HIF-1α -GLUT-1

0.02

0.437

0.625

-0.087

GLUT-1 - Ob

0.930

0.018

0.431

0.152

GLUT-1 - ObR

0.472

0.139

0.338

-0.165

GLUT-1 - ERα

0.022

-0.410

0.038

-0.337

GLUT-1 - ERβ

0.008

0.467

0.281

0.179

GLUT-1 - Ki-67

0.017

0.433

0.050

0.320

  1. n - number of studied cases.