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Table 1 IC50 values for doxorubicin and paclitaxel

From: TTFields alone and in combination with chemotherapeutic agents effectively reduce the viability of MDR cell sub-lines that over-express ABC transporters

 

IC50

Drug

AA8

EmtR1

MCF-7

MCF-7/Mx

MDA-MB-231

MDA-MB-231/Dox

Doxorubicin (μM)

0.6

48.4

0.5

30.5

0.04

2.2

Paclitaxel (μM)

0.1

65.3

0.09

9.9

0.005

0.829

  1. Drug concentrations inhibiting cell growth by 50% (IC50) were calculated from relative survival curves (see Figure 2) using the median-effect principle [16].
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BMC Cancer

ISSN: 1471-2407

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