Table 6 Stratified analysis of association by histology between the genotypes (alleles) and risk of glioma

Astrocytoma ^a

GG

121/366

1(Reference)

1(Reference)

1(Reference)

GA

112/276

0.182

1.23(0.91-1.66)

0.186

1.23(0.91-1.66)

0.092

1.32(0.96-1.81)

AA

22/51

0.335

1.31(0.76-2.24)

0.327

1.31(0.76-2.25)

0.285

1.37(0.77-2.43)

Additive

0.153

1.18(0.94-1.47)

0.152

1.18(0.94-1.48)

0.089

1.23(0.97-1.56)

G

354/1008

1(Reference)

#

A

156/378

0.155

1.18(0.94-1.47)

Glioblastoma

GG

94/366

1(Reference)

1(Reference)

1(Reference)

GA

99/276

0.042

1.40(1.01-1.93)

0.020

1.49(1.06-2.08)

0.024

1.51(1.06-2.17)

AA

27/51

0.006

2.06(1.23-3.46)

0.010

2.035(1.19-3.49)

0.003

2.354(1.34-4.15)

Additive

0.003

1.42(1.13-1.79)

0.002

1.45(1.14-1.84)

0.001

1.53(1.18-1.97)

G

287/1008

1(Reference)

#

A

153/378

0.003

1.42(1.13-1.79)

Other gliomas ^b

GG

83/366

1(Reference)

1(Reference)

1(Reference)

GA

94/276

0.017

1.50(1.08-2.10)

0.017

1.50(1.08-2.10)

0.028

1.96(1.08-3.58)

AA

20/51

0.059

1.73(0.98-3.06)

0.055

1.75(0.99-3.10)

0.003

1.71(1.20-2.45)

Additive

0.009

1.38(1.09-1.76)

0.008

1.39(1.09-1.77)

0.002

1.51(1.17-1.95)

G

260/1008

1(Reference)

#

A

134/378

0.009

1.37(1.08-1.75)