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Table 1 Clinicopathological characteristics of patients with non-small cell lung cancer (n = 99)

From: The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer

Variable

N = 99

5-yr survival (%)

Age years median (range)

60 ( 37 - 80)

Overall

Gender (male: female)

80:19

32

Tumor stage:

  

   I

35

49

   II

20

35

   III

34

19

   IV

10

10

Histology

  

   Adenocarcinoma

45

22

   Squamous cell carcinoma

51

41

   Large cell carcinoma

3

33

Tumor grade

  

   Well differentiation

3

67

   Moderate differentiation

48

40

   Poor differentiation

29

24

   Not recorded

19

20

Lymph node metastasis

  

   No

59

44

   Yes

40

15

  1. Histological criteria for the tumor grading:
  2. Adenocarcinomas:
  3. Well differentiation: glandular lumens are large and similar in sizes, with less cytologic atypia.
  4. Moderate differentiation: glandular lumens vary in sizes, with obvious cytologic atypia.
  5. Poor differentiation: glandular lumens are small or absent, with obvious cytologic atypia and mitosis.
  6. Squamous cell carcinomas:
  7. Well differentiation: ≥ 20% of the tumor islets has pearl formation.
  8. Moderate differentiation: < 20% of the tumor islets has pearl formation.
  9. Poor differentiation: no pearl formation in the tumor islets; only shows intracellular keratinization.
  10. Large cell carcinomas: by definition, are poorly differentiated tumors that lack the cytologic and architectural features of small cell carcinoma, squamous cell carcinoma, or adenocarcinoma.
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BMC Cancer

ISSN: 1471-2407

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