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Table 1 Clinical and pathological characteristic of the breast cancer patients

From: Hypermethylated 14-3-3-σ and ESR1 gene promoters in serum as candidate biomarkers for the diagnosis and treatment efficacy of breast cancer metastasis

Characteristics

Disease-Free Breast Cancer Group

Metastatic Breast Cancer Group

Histological type

  

Invasive ductal carcinoma

63 (81.8%)

22 (64.7%)

Invasive lobular carcinoma

8 (10.4%)

6 (17.6%)

Other invasive carcinoma

6 (7.8%)

4 (11.4%)

Unknown

0

2 (5.8%)

Histological grade

  

Grade I

17 (22.1%)

1 (2.9%)

Grade II

25 (32.5%)

8 (23.5%)

Grade III

26 (33.8%)

20 (58.8%)

Unknown

9 (11.7%)

5 (14.7%)

Tumor size

  

Tis

2 (2.6%)

1 (2.9%)

T1

40 (52.0%)

10 (29.4%)

T2

24 (31.2%)

13 (38.2%)

T3

7 (9.1%)

5 (14.7%)

T4

4 (5.2%)

2 (5.8%)

Tx

0

1 (2.9%)

Unknown

 

2 (5.8%)

Node involvement

  

N0

41 (53.3%)

13 (38.2%)

N1

26 (33.8%)

8 (23.5%)

N2

6 (7.8%)

9 (26.4%)

N3

3 (3.9%)

2 (5.8%)

Nx

1 (1.3%)

2 (5.8%)

Estrogen receptor status

  

Negative

20 (25.1%)

10 (27.7%)

Positive

53 (68.8%)

21 (61.7%)

Unknown

4 (5.2%)

3 (8.8%)

Progesterone receptor status

  

Negative

23 (30.0%)

10 (29.4%)

Positive

50 (64.9%)

22 (64.7%)

Unknown

4 (5.1%)

2 (5.8%)

Menopause

  

Yes

46 (62.3%)

31 (91.1%)

No

26 (33.8%)

 

Unknown

3 (3.9%)

3 (8.8%)