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Table 4 Risk of breast cancer in relation to serum concentrations of organochlorines in quartiles by estrogen receptor status.

From: Organochlorine exposures influence on breast cancer risk and survival according to estrogen receptor status: a Danish cohort-nested case-control study

Organochlorines

Estrogen receptor positive

Estrogen receptor negative

in quartiles (ng/mL)

Cases/controls

Adjusted RR (95% CI)a

p trendb

Cases/controls

Adjusted OR (95% CI)

p trend

HCB

I

<206.50

36/56

1.0 ref.c

 

19/23

1.0

 

II

206.50-269.75

20/55

1.1 (0.6-1.8)

 

8/23

0.5 (0.2-1.4)

 

III

269.75-335.75

22/56

1.0 (0.6-1.7)

 

11/23

0.8 (0.3-2.2)

 

IV

>335.75

36/55

1.2 (0.7-2.1)

>0.20

6/23

0.4 (0.1-1.4)

>0.20

Dieldrin

I

<12.01

27/57

1.0

 

6/23

1.0

 

II

12.01-28.30

28/56

1.3 (0.7-2,2)

 

5/23

1.2 (0.3-5.4)

 

III

28.30-57.11

33/57

1.5 (0.8-2.7)

 

13/23

4.9 (0.9-28.3)

 

IV

>57.11

28/56

1.4 (0.8-2.5)

>0.20

20/23

7.6 (1.3-46.1)

0.01

ΣPCB

I

<811.11

36/57

1.0

 

14/23

1.0

 

II

811.11-1076.04

24/56

1.1 (0.6-1.7)

 

11/23

1.0 (0.4-2.7)

 

III

1076.04-1405.73

20/57

0.7 (0.4-1.2)

 

11/23

1.3 (0.4-3.9)

 

IV

>1405.73

36/56

1.3 (0.8-2.2)

>0.20

8/23

0.8 (0.3-2.6)

>0.20

p,p'-DDE

I

<741.04

33/57

1.0

 

14/23

1.0

 

II

741.04-1129.75

29/56

0.7 (0.4-1.2)

 

11/23

0.9 (0.3-2.5)

 

III

1129.75-1688.85

25/57

0.8 (0.5-1.3)

 

10/23

0.7 (0.2-2.0)

 

IV

>1688.85

29/56

0.9 (0.6-1.5)

>0.20

9/23

0.6 (0.2-1.7)

>0.20

  1. a Odds ratio, 95% confidence interval, adjusted for age, weight, parity, and hormone replacement therapy; b two sided p-value for linear trend in OR's; c reference category. Cases with missing information on confounders were excluded.
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