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  1. Combination therapy is the primary treatment for unresectable hepatocellular carcinoma (u-HCC). The hepatic functional reserve is also critical in the treatment of HCC. In this study, u-HCC was treated with co...

    Authors: Yongqiang Xiao, Wei Deng, Laihui Luo, Guoqing Zhu, Jin Xie, Yu Liu, Renhua Wan, Wu Wen, Zhigao Hu and Renfeng Shan
    Citation: BMC Cancer 2024 24:588
    Content type: Research Published on:

  2. YAP and TAZ, the Hippo pathway terminal transcriptional activators, are frequently upregulated in cancers. In tumor cells, they have been mainly associated with increased tumorigenesis controlling different as...

    Authors: Věra Slaninová, Lisa Heron-Milhavet, Mathilde Robin, Laura Jeanson, Adam Aissanou, Diala Kantar, Diego Tosi, Laurent Bréhélin, Céline Gongora and Alexandre Djiane
    Citation: BMC Cancer 2024 24:587
    Content type: Research Published on:

  3. Observational study investigated the association between pernicious anemia (PA) and cancers. However, with the exception of gastric cancer, the results are mostly contradictory. The purpose of this study was t...

    Authors: Bangwei Che, Shenglan Yuan, Hongyan Zhang, Jiancheng Zhai, Yang Zhang, Chuanchuan Wu and Kaifa Tang
    Citation: BMC Cancer 2024 24:586
    Content type: Research Published on:

  4. The optimal timing for surgery following neoadjuvant immunochemotherapy for lung squamous cell carcinoma appears to be a topic of limited data. Many clinical studies lack stringent guidelines regarding this ti...

    Authors: Chen Gu, Xiao Teng, Xuqi sun, Jiacong Liu, Ziyue Zhu, Lichen Zhang, Zhigang Wu, Rui Zou, Jinghua Pang and Xiayi Lyu
    Citation: BMC Cancer 2024 24:585
    Content type: Research Published on:

  5. In chronic lymphocytic leukaemia (CLL), comorbidities assessed by the CLL comorbidity index (CLL-CI) have been associated with outcomes in Western cohorts. We conducted a retrospective analysis of an unselecte...

    Authors: Salem H. Alshemmari, Ahmad AlSarraf, Andy Kaempf and Alexey V. Danilov
    Citation: BMC Cancer 2024 24:584
    Content type: Research Published on:

  6. Insufficient evidence existed about the prognostic role of the advanced lung cancer inflammation index (ALI) for gastric cancer patients who underwent curative resection. The aim of this study was to identify ...

    Authors: Huayang Pang, Lingyan Dai, Lihui Chen, Xiufeng Chen, Zhixiong Chen, Shouru Zhang and Hao Sun
    Citation: BMC Cancer 2024 24:583
    Content type: Research Published on:

  7. Local recurrence after surgery and radiochemotherapy seriously affects the prognosis of locally advanced rectal cancer (LARC) patients. Studies on molecular markers related to the radiochemotherapy sensitivity...

    Authors: Heng Zhang, Xiaofan Li, Wanjun Sun, Haoren Qin, Haipeng Li, Hao Yan, Huaqing Wang, Xipeng Zhang, Shiwu Zhang and Hui Wang
    Citation: BMC Cancer 2024 24:582
    Content type: Research Published on:

  9. SRSF1, a member of Serine/Arginine-Rich Splicing Factors (SRSFs), has been observed to significantly influence cancer progression. However, the precise role of SRSF1 in osteosarcoma (OS) remains unclear. This ...

    Authors: Shuqi Li, Xinyi Huang, Shuang Zheng, Wenhui Zhang, Fang Liu and Qinghua Cao
    Citation: BMC Cancer 2024 24:580
    Content type: Research Published on:

  11. This study aims to develop a nomogram integrating inflammation (NLR), Prognostic Nutritional Index (PNI), and EBV DNA (tumor burden) to achieve personalized treatment and prediction for stage IVA NPC. Furtherm...

    Authors: Yuhui pan, Zihan Chen, Wenquan Hong, Zongwei Huang, Ying Li, Sunqin Cai, Jinghua Lai, Jun Lu and Sufang Qiu
    Citation: BMC Cancer 2024 24:578
    Content type: Research Published on:

  12. Soft-tissue metastasis of carcinoma is rare. In the present study, we investigated the surgical indications and clinical features of patients with soft tissue metastases of carcinoma.

    Authors: Sei Morinaga, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Yohei Asano, Takayuki Nojima and Hiroyuki Tsuchiya
    Citation: BMC Cancer 2024 24:577
    Content type: Research Published on:

  13. Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with special biological features. Controversies exist regarding the treatment approach and prognostic factors in the IMRT era. This study aim...

    Authors: Wen-Bin Wu, Wu-Lin Cai, Ye-Hao Zou, Rui You, You-Ping Liu, Zhao-Di Yuan, Qiong Li, Wen-Chao Li, Zhi-Xuan Pi, Yu-Long Xie, Kai Wen, Ming-Yuan Chen and Rui Sun
    Citation: BMC Cancer 2024 24:576
    Content type: Research Published on:

  14. To identify the risk factors of cervical high-grade squamous intraepithelial lesion(HSIL) complicated with occult cervical cancer and standardize the management of initial treatment for HSIL.

    Authors: Lingyu Lei, Lin Zhang, Yahong Zheng, Wei Ma, Fang Liu, Dongmei Li, Keming Chen and Yong Zeng
    Citation: BMC Cancer 2024 24:575
    Content type: Research Published on:

  15. Next-generation sequencing (NGS) has been introduced to many Korean institutions to support molecular diagnostics in cancer since 2017, when it became eligible for reimbursement by the National Health Insuranc...

    Authors: Sun Young Kim, Jee Hyun Kim, Tae-Yong Kim, Sook Ryun Park, Shinkyo Yoon, Soohyeon Lee, Se-Hoon Lee, Tae Min Kim, Sae-Won Han, Hye Ryun Kim, Hongseok Yun, Sejoon Lee, Jihun Kim, Yoon-La Choi, Kui Son Choi, Heejung Chae…
    Citation: BMC Cancer 2024 24:574
    Content type: Study Protocol Published on:

  16. Microsatellite instability-high (MSI-H) has emerged as a significant biological characteristic of colorectal cancer (CRC). Studies reported that MSI-H CRC generally had a better prognosis than microsatellite s...

    Authors: Junwen Cai, Yuting Yang, Leilei Zhang, Yangyang Fang, Yanjun Zhang, Mingyue Tan, Juan Zhang, Chen Tang, Haitao Ren, Lanni Wang, Guangxin Xiang, Feng Xu, Linhua Lan, Liyi Li and Xiaoqun Zheng
    Citation: BMC Cancer 2024 24:573
    Content type: Research Published on:

  17. Postoperative central diabetes insipidus (CDI) is commonly observed in craniopharyngioma (CP) patients, and the inflammatory response plays an important role in CPs. We aimed to evaluate the predictive value o...

    Authors: Jing Wang, Guanghui Wang, Lidong Cheng, Hongtao Zhu, Junwen Wang, Xinmin Ding, Hongquan Niu, Kai Zhao and Kai Shu
    Citation: BMC Cancer 2024 24:572
    Content type: Research Published on:

  18. Glycometabolism and lipid metabolism are critical in cancer metabolic reprogramming. The primary aim of this study was to develop a prognostic model incorporating glycometabolism and lipid metabolism-related g...

    Authors: Xuefen Lin, Jianfeng Zheng, Xintong Cai, Li Liu, Shan Jiang, Qinying Liu and Yang Sun
    Citation: BMC Cancer 2024 24:571
    Content type: Research Published on:

  19. Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide and is associated with high morbidity and mortality rates. However, the specific biomarkers used to predict the postoperative prognos...

    Authors: Shuchang Wang, Weifeng Zhang, Xinrui Wu, Zhu Zhu, Yuanbiao Chen, Wangrui Liu, Junnfei Xu, Li Chen and Chun Zhuang
    Citation: BMC Cancer 2024 24:570
    Content type: Research Published on:

  20. No definite conclusion has yet to be reached for immunotherapy beyond progression(IBP) of first-line immunotherapy as the second-line treatment for advanced NSCLC patients with negative driver genes. Therefore...

    Authors: Min Wang, Xuquan Jing, Feihu Chen, Shuangqing Lu and Yulan Sun
    Citation: BMC Cancer 2024 24:569
    Content type: Research Published on:

  21. The index composed of preoperative lymphocytes, albumin, and neutrophils (LANR), a new composite score based on inflammatory response and nutritional status, has been reported to be associated with the prognos...

    Authors: Jiaru Zhuang, Shan Wang, Yuan Wang, Yibo Wu and Renjing Hu
    Citation: BMC Cancer 2024 24:568
    Content type: Research Published on:

  22. Pyroptosis is a type of programmed cell death mediated by the gasdermin family. Gasdermin B (GSDMB), as a member of gasdermin family, can promote the occurrence of cell pyroptosis. However, the correlations of...

    Authors: Liang Sun, Jiahui Wang, Yuxuan Li, Yixin Kang, Yi Jiang, Jun Zhang, Senmi Qian and Fangying Xu
    Citation: BMC Cancer 2024 24:567
    Content type: Research Published on:

  23. Resveratrol has demonstrated its ability to regulate BRCA1 gene expression in breast cancer cells, and previous studies have established the binding of MBD proteins to BRCA1 gene promoter regions. However, the mo...

    Authors: Ram Krishna Sahu, Simran Tandon, Shalini Singh, Bhudev Chandra Das and Suresh T Hedau
    Citation: BMC Cancer 2024 24:566
    Content type: Research Published on:

  24. Recent studies showed heterogeneity in stage IVB patients. However, few studies focused on the prognosis of supraclavicular metastatic ovarian cancer. This study aimed to explore the prognostic factors and the...

    Authors: Chenlian Quan, Xiaojun Chen, Hao Wen, Xiaohua Wu and Jin Li
    Citation: BMC Cancer 2024 24:565
    Content type: Research Published on:

  25. 5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. There...

    Authors: Xuyang Zhang, Kairui Sun, Ruihuan Gan, Yuxiang Yan, Chaochao Zhang, Dali Zheng and Youguang Lu
    Citation: BMC Cancer 2024 24:564
    Content type: Research Published on:

  26. Authors: Monica Niger, Federico Nichetti, Lorenzo Fornaro, Chiara Pircher, Federica Morano, Federica Palermo, Lorenza Rimassa, Tiziana Pressiani, Rossana Berardi, Andrea Casadei Gardini, Elisa Sperti, Lisa Salvatore, Davide Melisi, Francesca Bergamo, Salvatore Siena, Stefania Mosconi…
    Citation: BMC Cancer 2024 24:563
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2024 24:436

  28. Modulation of DNA damage repair in lung squamous cell carcinoma (LUSC) can result in the generation of neoantigens and heightened immunogenicity. Therefore, understanding DNA damage repair mechanisms holds sig...

    Authors: Lu Xia, Hexin Lin, Huifen Cao and Jiabian Lian
    Citation: BMC Cancer 2024 24:561
    Content type: Research Published on:

  29. Developing countries have a significantly higher incidence of breast cancer in patients younger than 40 years as compared to developed countries. This study aimed to examine if young age at diagnosis is an ind...

    Authors: Eman Sbaity, Hani Tamim, Ghada El-Hajj Fuleihan, Jaber Abbas, Mariam Zahwe, Razan El Sayed and Ali Shamseddine
    Citation: BMC Cancer 2024 24:560
    Content type: Research Published on:

  30. In contrast to the decreasing trends in developed countries, the incidence and mortality rates of cervical squamous cell carcinoma in China have increased significantly. The screening and identification of rel...

    Authors: Aiqin Zhao, Yunzhi Pan, Yingyin Gao, Zheng Zhi, Haiying Lu, Bei Dong, Xuan Zhang, Meiying Wu, Fenxia Zhu, Sufang Zhou and Sai Ma
    Citation: BMC Cancer 2024 24:559
    Content type: Research Published on:

  31. Portal hypertension (PHT) has been proven to be closely related to the development of hepatocellular carcinoma (HCC). Whether PHT before liver transplantation (LT) will affect the recurrence of HCC is not clear.

    Authors: Guo Wei, Yong Zhao, Shifeng Feng, Jingsheng Yuan, Gang Xu, Tao Lv, Jian Yang, Lingxiang Kong and Jiayin Yang
    Citation: BMC Cancer 2024 24:558
    Content type: Research Published on:

  32. While radiation therapy remains pivotal in esophageal squamous cell carcinoma (ESCC) treatment, the perplexing phenomenon of post-radiation metastasis presents a formidable clinical challenge. This study inves...

    Authors: Shan Huang, Jiayi Zhang, Pu He, Xinyue Cui, Yuzhu Hou, Wanghui Su and Fang Li
    Citation: BMC Cancer 2024 24:557
    Content type: Research Published on:

  33. Radiotherapy is a mainstay of cancer treatment. The clinical response to radiotherapy is heterogeneous, from a complete response to early progression. Recent studies have explored the importance of patient cha...

    Authors: Venkata SK. Manem and Farzad Taghizadeh-Hesary
    Citation: BMC Cancer 2024 24:556
    Content type: Editorial Published on:

  34. Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio-, and duodenal carcinoma, are frequently diagnosed in an advanced stage and are associated with poor overall survival. T...

    Authors: Stina Margrethe Stålberg, Laxmi Silwal-Pandit, Nasser Ezzatkhah Bastani, Daniel Johan Hammer Nebdal, Ole Christian Lingjærde, Bjørn Steen Skålhegg and Elin Hegland Kure
    Citation: BMC Cancer 2024 24:555
    Content type: Research Published on:

  35. Prostate cancer is dependent on androgen receptor (AR) signaling, and androgen deprivation therapy (ADT) has proven effective in targeting prostate cancer. However, castration-resistant prostate cancer (CRPC) ...

    Authors: Daisuke Obinata, Kenichi Takayama, Mitchell G Lawrence, Daigo Funakoshi, Makoto Hara, Birunthi Niranjan, Linda Teng, Renea A Taylor, Gail P Risbridger, Satoru Takahashi and Satoshi Inoue
    Citation: BMC Cancer 2024 24:554
    Content type: Research Published on:

  36. Cancer incidence is increasing in Ethiopia mainly due to increased life expectancy, while oncological capacities remain limited. Strong referral linkages between different levels of the healthcare system are k...

    Authors: Josephin Trabitzsch, Morena Marquardt, Sarah Negash, Winini Belay, Yonas Abebe, Edom Seife, Kunuz Abdella, Muluken Gizaw, Sefonias Getachew, Adamu Addissie, Eva Johanna Kantelhardt and Abigiya Wondimagegnehu
    Citation: BMC Cancer 2024 24:553
    Content type: Research Published on:

  39. Long nonconding RNAs (lncRNAs) have been found to be a vital regulatory factor in the development process of human cancer, and could regarded as diagnostic or prognostic biomarkers for human cancers. Here, we ...

    Authors: Shiping Huang, Zhouxiang Liao, Xiao He, Zhenyu Song, Xi Fang, Sha Wen, Lichao Yang, Hui Li, Qi Zhang, Wanling Mo, Xiaojing Cheng, Min He and Xuejing Huang
    Citation: BMC Cancer 2024 24:550
    Content type: Research Published on:

  40. Accurate assessment of axillary status after neoadjuvant therapy for breast cancer patients with axillary lymph node metastasis is important for the selection of appropriate subsequent axillary treatment decis...

    Authors: Jia Wang, Cong Tian, Bing-Jie Zheng, Jiao Zhang, De-Chuang Jiao, Jin-Rong Qu and Zhen-Zhen Liu
    Citation: BMC Cancer 2024 24:549
    Content type: Research Published on:

  41. For patients with early-stage cervical cancer without high-risk factors, there is no consensus regarding the optimal postoperative treatment regimen and whether postoperative concurrent radiochemotherapy (CCRT...

    Authors: Yuncan Zhou, Weiping Wang, Jia Tang, Ke Hu and Fuquan Zhang
    Citation: BMC Cancer 2024 24:548
    Content type: Research Published on:

  42. The purpose of this study was to develop an individual survival prediction model based on multiple machine learning (ML) algorithms to predict survival probability for remnant gastric cancer (RGC).

    Authors: Zhouwei Zhan, Bijuan Chen, Hui Cheng, Shaohua Xu, Chunping Huang, Sijing Zhou, Haiting Chen, Xuanping Lin, Ruyu Lin, Wanting Huang, Xiaohuan Ma, Yu Fu, Zhipeng Chen, Hanchen Zheng, Songchang Shi, Zengqing Guo…
    Citation: BMC Cancer 2024 24:547
    Content type: Research Published on:

  43. Cancer survival and mortality outcomes for people with mental health and substance use conditions (MHSUC) are worse than for people without MHSUC, which may be partly explained by poorer access to timely and a...

    Authors: Ruth Cunningham, James Stanley, Fiona Imlach, Tracy Haitana, Helen Lockett, Susanna Every-Palmer, Mau Te Rangimarie Clark, Cameron Lacey, Kendra Telfer and Debbie Peterson
    Citation: BMC Cancer 2024 24:546
    Content type: Research Published on:

  44. Cancer survivors have a high risk of mortality, and vitamin D (VD) is associated with the risk of mortality. This study is aim to examine the impact of VD on mortality in cancer survivors.

    Authors: Xiaofei Mo, Chen He, Fengfeng Han, Hui Yan, Xueqin Chen, Yuetao Wang and Mingge Zhou
    Citation: BMC Cancer 2024 24:545
    Content type: Research Published on:

  46. This study aimed to evaluate the prognostic significance of postoperative Creatine Kinase type M and B (CK-MB) to total Creatine Kinase (CK) ratio (CK-MB/CK) in colorectal cancer (CRC) patients after radical r...

    Authors: Lubei Rao, Pingyao Xu, Guiji Zhang, Ruiling Zu, Yajun Luo, Kaijiong Zhang, Ying Yang, Dongsheng Wang, Shuya He, Huaichao Luo and Bo Ye
    Citation: BMC Cancer 2024 24:543
    Content type: Research Published on:

  48. The goal of the research was to assess the quantitative relationship between median progression-free survival (PFS) and median overall survival (OS) specifically among patients with relapsed/refractory multipl...

    Authors: Meletios Dimopoulos, Pieter Sonneveld, Salomon Manier, Annette Lam, Tito Roccia, Jordan M. Schecter, Patricia Cost, Lida Pacaud, Abbey Poirier, Gabriel Tremblay, Tommy Lan, Satish Valluri and Shaji Kumar
    Citation: BMC Cancer 2024 24:541
    Content type: Research Published on:

  50. There is no updated national data regarding the real impact of the COVID-19 pandemic on delaying diagnosis and treatment among patients with lung, and head, and neck cancers in Brazil. This study aimed to anal...

    Authors: Gilson Gabriel Viana Veloso, Flávia Duarte Amaral and Angélica Nogueira-Rodrigues
    Citation: BMC Cancer 2024 24:539
    Content type: Research Published on:

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