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Table 1 The IC50 (μM) of curcumin and its analogues, GO-Y030, FLLL-11, and FLLL-12 in human colon cancer cells and WI-38 human lung fibroblasts

From: New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

 

HCT116

(IC50 μM)

HT-29

(IC50 μM)

SW480

(IC50 μM)

WI-38

(IC50 μM)

Curcumin

10.91

13.31

10.26

48.82

GO-Y030

0.61

0.96

0.51

13.78

FLLL-11

2.07

4.48

1.64

>1000.00

FLLL-12

2.49

3.35

1.17

>1000.00

  1. *Cancer cells were treated for 72 hours and cell viability was determined by MTT assays and IC50 values were analyzed.
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BMC Cancer

ISSN: 1471-2407

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