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  1. Associations between reproductive factors and breast cancer (BC) risk vary by molecular subtype (i.e., luminal A, luminal B, HER2, and triple negative/basal-like [TNBC]). In this systematic review and meta-ana...

    Authors: Xihua Mao, Chioma Omeogu, Shama Karanth, Ashwini Joshi, Clare Meernik, Lauren Wilson, Amy Clark, April Deveaux, Chunyan He, Tisha Johnson, Karen Barton, Samantha Kaplan and Tomi Akinyemiju
    Citation: BMC Cancer 2023 23:644
    Content type: Research Published on:

  2. With the availability of health insurance claim data, pharmacovigilance for various drugs has been suggested; however, it is necessary to establish an appropriate analysis method. To detect unintended drug eff...

    Authors: Hyeong-Taek Woo, Seung-Yong Jeong and Aesun Shin
    Citation: BMC Cancer 2023 23:643
    Content type: Research Published on:

  4. The impact of sarcopenia on the outcome of patients with left-sided colon and rectal cancer has not been exhaustively investigated. Thus, the present study was performed to evaluate the effect of sarcopenia on...

    Authors: Qi Li, Tailai An, Jianbin Wu, Weiqi Lu, Yan Wang, Jia Li, Lina Yang, Yiqi Chen, Lizhu Lin and Zhenjiang Yang
    Citation: BMC Cancer 2023 23:640
    Content type: Research Published on:

  5. Synovial sarcoma (SS) is one of the commonest non-rhabdomyosarcoma soft tissue sarcoma with limited treatment options in the relapsed and advanced settings. The combination of gemcitabine and docetaxel has dem...

    Authors: Ghazal Tansir, Sameer Rastogi, Akash Kumar, Adarsh Barwad, Asit R. Mridha, Ekta Dhamija, Shamim A. Shamim, Sushma Bhatnagar and Sandeep Bhoriwal
    Citation: BMC Cancer 2023 23:639
    Content type: Research Published on:

  6. To explore the value of a multiparametric magnetic resonance imaging (MRI)-based deep learning model for the preoperative prediction of Ki67 expression in prostate cancer (PCa).

    Authors: Shuitang Deng, Jingfeng Ding, Hui Wang, Guoqun Mao, Jing Sun, Jinwen Hu, Xiandi Zhu, Yougen Cheng, Genghuan Ni and Weiqun Ao
    Citation: BMC Cancer 2023 23:638
    Content type: Research Published on:

  7. Hepatocellular carcinoma (HCC) is one of the most common human cancers with poor prognosis in the world. HCC has become the second leading cause of cancer-related death in China. It is urgent to identify novel...

    Authors: Yuchen Qi, Yujing Zhang, Jianwen Li, Mengting Cai, Bo Zhang, Zhangtao Yu, Yuhang Li, Junkai Huang, Xu Chen, Yinghui Song and Sulai Liu
    Citation: BMC Cancer 2023 23:637
    Content type: Research Published on:

  9. Atezolizumab plus bevacizumab was approved in 2020 as a first-line treatment for advanced hepatocellular carcinoma (HCC). The purpose of this study was to assess the curative effect and tolerability of the com...

    Authors: Xiaoqiang Gao, Rui Zhao, Huaxing Ma and Shi Zuo
    Citation: BMC Cancer 2023 23:635
    Content type: Research Published on:

  10. Few studies have focused on the impact of single-organ pulmonary metastases on progression-free survival and overall survival in patients with metastatic colorectal cancer. Recognizing differences in prognosis...

    Authors: Koshiro Fukuda, Hiroki Osumi, Koichiro Yoshino, Izuma Nakayama, Shota Fukuoka, Mariko Ogura, Takeru Wakatsuki, Akira Ooki, Daisuke Takahari, Keisho Chin, Kensei Yamaguchi and Eiji Shinozaki
    Citation: BMC Cancer 2023 23:634
    Content type: Research Published on:

  11. Low levels of cancer awareness may contribute to delays in seeking medical help and subsequent delays in diagnosis. For blood cancer this may be a particularly prominent problem due to the high prevalence of u...

    Authors: Laura Boswell, Jenny Harris, Athena Ip, Jessica Russell, Georgia B Black and Katriina L Whitaker
    Citation: BMC Cancer 2023 23:633
    Content type: Research Published on:

  12. Aromatase inhibitors (AI) are frequently used to treat hormone-receptor-positive breast cancer, but they have multiple adverse effects (e.g., osteoporosis, arthralgia), resulting in premature therapy discontin...

    Authors: Eliana V. Carraça, Bruno Rodrigues, Sofia Franco, Inês Nobre, Flávio Jerónimo, Vítor Ilharco, Fernanda Gabriel, Leonor Ribeiro, António L. Palmeira and Marlene N. Silva
    Citation: BMC Cancer 2023 23:632
    Content type: Study Protocol Published on:

  13. Cervical cancer is one of the most common cancers and a major cause of morbidity among women globally. Chemoradiation therapy is the preferred standard treatment for women with stage IB to IVA. However, the be...

    Authors: Josephine Irene Najjemba, Regina Ndagire, Pius Mulamira, Solomon Kibudde and Catherine Nassozi Lwanira
    Citation: BMC Cancer 2023 23:631
    Content type: Research Published on:

  14. Multiple myeloma is a heterogeneous disorder and the intratumor genetic heterogeneity contributes to emergency of drug resistance. Dexamethasone has been used clinically for decades for MM. Nevertheless, their...

    Authors: Yuyue Ren, Yijun Liu, Wanting He, Weiwei Zhao, Jiaqi Pan, Haiyan Gao, Yuying Li, Ying Zhang and Wei Wang
    Citation: BMC Cancer 2023 23:630
    Content type: Research Published on:

  15. To include the patient perspective in the assessment of adverse events in oncology, a patient-reported outcomes (PRO) version of the Common Terminology Criteria for Adverse Events (CTCAE) was developed by the ...

    Authors: Maximilian Günther, Leopold Hentschel, Markus Schuler, Theresa Müller, Katharina Schütte, Yon-Dschun Ko, Ingo Schmidt-Wolf and Ulrich Jaehde
    Citation: BMC Cancer 2023 23:629
    Content type: Research Published on:

  17. The COVID-19 pandemic has affected all aspects of the healthcare system, including prevention, treatment, rehabilitation of diseases and health education; access to essential therapies; allocation of finance &...

    Authors: Amir Sadeghi, Hamid Asadzadeh Aghdaei, Mohammad Amin Khalafi, Ehsan Nazemalhosseini-Mojarad, Pardis Ketabi Moghadam and Mohammad-Reza Sohrabi
    Citation: BMC Cancer 2023 23:627
    Content type: Research Published on:

  18. CXC-chemokine receptor 2 (CXCR2) expression was found to be down-regulated on circulating monocytes of cancer patients. Here, we analyze the percentage of CD14+CXCR2+ monocyte subsets in hepatocellular carcinoma ...

    Authors: Chong Zhong Liu, Xing Bao Liu, Jun Sun, Chao Qun Yu, Jing Chun Yao, Zhong Liu and Jing Cheng Hao
    Citation: BMC Cancer 2023 23:626
    Content type: Research Published on:

  19. Adjuvant endocrine treatment is essential for treating luminal subtypes of breast cancer, which constitute 75% of all breast malignancies. However, the detrimental side effects of treatment make it difficult f...

    Authors: Finn Magnus Eliassen, Vibeke Blåfjelldal, Thomas Helland, Cathrine Fonnesbech Hjorth, Kari Hølland, Lise Lode, Bjørn-Erik Bertelsen, Emiel A. M. Janssen, Gunnar Mellgren, Jan Terje Kvaløy, Håvard Søiland and Tone Hoel Lende
    Citation: BMC Cancer 2023 23:625
    Content type: Research Published on:

  20. Locally advanced pancreatic ductal adenocarcinoma (PDAC), accounting for about 30% of PDAC patients, is difficult to cure by radical resection or systemic chemotherapy alone. A multidisciplinary strategy is re...

    Authors: Osamu Shimomura, Masato Endo, Hirokazu Makishima, Takeshi Yamada, Shinji Hashimoto, Haruko Numajiri, Yoshihiro Miyazaki, Manami Doi, Kinji Furuya, Kazuhiro Takahashi, Toshikazu Moriwaki, Naoyuki Hasegawa, Yoshiyuki Yamamoto, Yusuke Niisato, Mariko Kobayashi, Masashi Mizumoto…
    Citation: BMC Cancer 2023 23:624
    Content type: Study protocol Published on:

  21. Cancer is highly prevalent worldwide. Family resilience is a positive variable that helps families burdened by advanced cancer to cope effectively. This study aimed to describe the family resilience of advance...

    Authors: Panpan Cui, Jiaoxia Shi, Shifeng Li, Mikiyas Amare Getu, Ruibo Wang and Changying Chen
    Citation: BMC Cancer 2023 23:623
    Content type: Research Published on:

  22. Lymph node metastasis (LNM) is an important factor affecting endometrial cancer (EC) prognosis. Current controversy exists as to how to accurately assess the risk of lymphatic metastasis. Metabolic syndrome ha...

    Authors: Xuan Feng, Xing Chen Li, Xiao Yang, Yuan Cheng, Yang Yang Dong, Jing Yuan Wang, Jing Yi Zhou and Jian Liu Wang
    Citation: BMC Cancer 2023 23:622
    Content type: Research Published on:

  23. Sensitive and reproducible detection of residual disease after treatment is a major challenge for patients with locally advanced head and neck cancer. Indeed, the current imaging techniques are not always reli...

    Authors: Angeline Ginzac, Marie-Céleste Ferreira, Anne Cayre, Clément Bouvet, Julian Biau, Ioana Molnar, Nicolas Saroul, Nathalie Pham-Dang, Xavier Durando and Maureen Bernadach
    Citation: BMC Cancer 2023 23:621
    Content type: Study Protocol Published on:

  24. Metabolic derangements and systemic inflammation are related to the progression of colorectal cancer (CRC) and the prognoses of these patients. The survival of stage II and III CRC patients existed considerabl...

    Authors: Jinming Fu, Fenqi Du, Tian Tian, Hao Huang, Lei Zhang, Dapeng Li, Yupeng Liu, Ding Zhang, Lijing Gao, Ting Zheng, Yanlong Liu and Yashuang Zhao
    Citation: BMC Cancer 2023 23:620
    Content type: Research Published on:

  26. Gene fusions are important cancer drivers in pediatric cancer and their accurate detection is essential for diagnosis and treatment. Clinical decision-making requires high confidence and precision of detection...

    Authors: Ianthe A. E. M. van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. P. Verwiel, Douwe F. M. van der Leest, Lennart Kester, Jan J. Molenaar, Jules Meijerink, Jarno Drost, Weng Chuan Peng, Hindrik H. D. Kerstens, Bastiaan B. J. Tops, Frank C. P. Holstege…
    Citation: BMC Cancer 2023 23:618
    Content type: Research article Published on:

  27. The prognosis of patients with colorectal cancer is related to early detection. However, commonly used screening markers lack sensitivity and specificity. In this study, we identified diagnostic methylation si...

    Authors: Zhen Ye, Guangle Song, Jianwei Liang, Shuying Yi, Yuqi Gao and Hanming Jiang
    Citation: BMC Cancer 2023 23:617
    Content type: Research Published on:

  28. To investigate the relationship among 18 heavy metals, microsatellite instability (MSI) status, ERCC1, XRCC1 (rs25487), BRAF V600E and 5 tumor markers and their role in the development of colorectal cancer (CRC).

    Authors: Yongsheng Li, Jingwei Lou, Shaozhong Hong, Dengfeng Hou, Yandong Lv, Zhiqiang Guo, Kai Wang, Yue Xu, Yufeng Zhai and Hongzhou Liu
    Citation: BMC Cancer 2023 23:616
    Content type: Research Published on:

  29. Insulin resistance is an overlapping risk factor for both heart and breast cancer, while its interaction with cardiotoxicity in breast cancer (BC) patients is not clear. This study investigated the impact of i...

    Authors: Yunjing Shi, Zeping Qiu, Jing Yu, Zhuojin Li, Sha Hua, Yanjia Chen, Xiaosong Chen, Kunwei Shen and Wei Jin
    Citation: BMC Cancer 2023 23:615
    Content type: Research Published on:

  30. Small extracellular vesicles (sEVs) have great potential as new biomarkers in liquid biopsy. However, due to the limitations of sEVs extraction and component analysis procedures, further clinical applications ...

    Authors: Yifan Sun, Miao Li, Xiaoshan Zhang, Dongjie Xu, Jie Wu, Xinrui Gu, Adeel Khan, Han Shen and Zhiyang Li
    Citation: BMC Cancer 2023 23:614
    Content type: Research Published on:

  31. Ovarian clear cell carcinomas (OCCCs) are rare, aggressive and chemoresistant tumors. Geographical and ethnic differences in the incidence of OCCC have been reported with a higher incidence in Asiatic countrie...

    Authors: Mariana de Paiva Batista, Martín Roffé, Ignacio Romero, José Antonio López-Guerrero, Carmen Illueca, Raquel Lopez, Alexandre André Balieiro Anastácio da Costa, Louise De Brot, Juan Pablo Molina, Laura Barboza, Fernanda Maris Peria, Fernando Chaud, Ana Silvia Gouvêa Yamada, Andres Poveda and Eduardo Magalhães Rego
    Citation: BMC Cancer 2023 23:613
    Content type: Research Published on:

  35. Even though chemotherapy-induced nausea and vomiting (CINV) can be well controlled in the acute phase, the incidence of delayed CINV remains high. In this study, we intend to investigate whether prolonged use ...

    Authors: Ai Gao, Shasha Guan, Yinjuan Sun, Lingling Wang, Fanlu Meng, Xia Liu, Liyan Gu, Guo Li, Diansheng Zhong and Linlin Zhang
    Citation: BMC Cancer 2023 23:609
    Content type: Research Published on:

  36. To assess the clinical characteristics and the risk factors related to the unfavorable prognosis of endometrioid ovarian carcinoma (EOVC) based on data from the Surveillance, Epidemiology, and End Results (SEE...

    Authors: Shuangfeng Chen, Huaiwu Lu, Shan Jiang, Min Li, Haiyan Weng, Jing Zhu, Tianjiao Zhang, Yingying Wang, Weidong Zhao, Dabao Wu, Zhen Shen, Zhenye Yang and Ying Zhou
    Citation: BMC Cancer 2023 23:608
    Content type: Research Published on:

  37. Single nucleotide polymorphism (SNP) is a genetic variation that occurs when a single nucleotide base in the DNA sequence varies between individuals and is present in at least 1% of the population. Genetic var...

    Authors: Ming-Ju Hsieh, Yu-Sheng Lo, Yun-Jung Tsai, Hsin-Yu Ho, Chia-Chieh Lin, Yi-Ching Chuang, Shu-Hui Lin and Mu-Kuan Chen
    Citation: BMC Cancer 2023 23:607
    Content type: Research Published on:

  38. Extending adjuvant endocrine therapy (ET) beyond the standard 5 years offers added protection against late breast cancer recurrences in women with early-stage hormone receptor-positive (HR +) breast cancer. Li...

    Authors: Julia Foldi, Anastasia Tsagianni, Max Salganik, Catherine A. Schnabel, Adam Brufsky, G. J. van Londen, Lajos Pusztai and Tara Sanft
    Citation: BMC Cancer 2023 23:606
    Content type: Research article Published on:

  39. Urothelial bladder cancer is most frequently diagnosed at the non-muscle-invasive stage (NMIBC). However, recurrences and interventions for intermediate and high-risk NMIBC patients impact the quality of life....

    Authors: Iliana K. Kerzeli, Alexandros Kostakis, Polat Türker, Per-Uno Malmström, Tammer Hemdan, Artur Mezheyeuski, Douglas G. Ward, Richard T. Bryan, Ulrika Segersten, Martin Lord and Sara M. Mangsbo
    Citation: BMC Cancer 2023 23:605
    Content type: Research Published on:

  40. Aspartoacylase (ASPA) is a gene that plays an important role in the metabolic reprogramming of cancer. However, the clinical relevance of ASPA in gastric cancer (GC) has not been demonstrated.

    Authors: Yalin Han, Xuning Wang, Maolin Xu, Zhipeng Teng, Rui Qin, Guodong Tan, Peng Li, Peng Sun, Hongyi Liu, Li Chen and Baoqing Jia
    Citation: BMC Cancer 2023 23:604
    Content type: Research Published on:

  41. The landscape of non-small cell lung cancer (NSCLC) therapy is rapidly changing. This analysis aimed to understand patient characteristics, diagnosis and treatment patterns in patients with metastatic NSCLC (m...

    Authors: Hollie Bailey, Adam Lee, Laura Eccles, Yong Yuan, Helen Burlison, Cameron Forshaw and Nebibe Varol
    Citation: BMC Cancer 2023 23:603
    Content type: Research Published on:

  42. The discovery of new anti-melanoma drugs with low side effect is urgently required in the clinic. Recent studies showed that morusin, a flavonoid compound isolated from the root bark of Morus Alba, has the pot...

    Authors: Wei Liu, Yacong Ji, Feng Wang, Chongyang Li, Shaomin Shi, Ruochen Liu, Qian Li, Leiyang Guo, Yaling Liu and Hongjuan Cui
    Citation: BMC Cancer 2023 23:602
    Content type: Research Published on:

  43. Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by challenging early diagnosis and poor prognosis. It is believed that coagulation has an impact on the tumor microenvironment of PDAC. The...

    Authors: Di Wang, Song-ping Cui, Qing Chen, Zhang-yong Ren, Shao-cheng Lyu, Xin Zhao and Ren Lang
    Citation: BMC Cancer 2023 23:601
    Content type: Research Published on:

  44. An assessment is being conducted to determine the safety and effectiveness of using Cone-beam computed tomography (CBCT)-guided transcatheter arterial chemoembolization (TACE) and microwave ablation (MWA) sequ...

    Authors: Zhaonan Li, Kaihao Xu, Xueliang Zhou, Dechao Jiao and Xinwei Han
    Citation: BMC Cancer 2023 23:600
    Content type: Research Published on:

  45. Dihydropyrimidinase-like 3 (DPYSL3) is a cytosolic phosphoprotein expressed in the nervous system and is crucial for neurogenesis. A previous study showed that increased DPYSL3 expression promotes tumour aggre...

    Authors: Peir-In Liang, Hong-Yue Lai, Ti-Chun Chan, Wei-Ming Li, Chung-Hsi Hsing, Steven K. Huang, Kun-Lin Hsieh, Wen-Hsin Tseng, Tzu-Ju Chen, Wan-Shan Li, Huan-Da Chen, Yu-Hsuan Kuo and Chien-Feng Li
    Citation: BMC Cancer 2023 23:599
    Content type: Research Published on:

  46. Over past decades, epidemiological patterns of liver cancer (LC) have changed dramatically. The Global Burden of Disease (GBD) study provides an opportunity for tracking the progress in cancer control with its...

    Authors: Yongzhi Li, Zejin Ou, Danfeng Yu, Huan He, Liting Zheng, Jiaqi Chen, Caiyun Chen, Hushen Xiong and Qing Chen
    Citation: BMC Cancer 2023 23:598
    Content type: Research Published on:

  47. The nutritional status of cancer patients is a crucial factor in determining their prognosis. The objective of this study was to investigate and compare the prognostic value of pretreatment nutrition-related i...

    Authors: Jianjian Qiu, Jun Yang, Yilin Yu, Zhiping Wang, Hancui Lin, Dongmei Ke, Hongying Zheng, Jiancheng Li and Qiwei Yao
    Citation: BMC Cancer 2023 23:597
    Content type: Research Published on:

  48. Glioma is the most common malignant primary brain tumor and is characterized by a poor prognosis and limited therapeutic options. ISG20 expression is induced by interferons or double-stranded RNA and is associ...

    Authors: Yaojun Peng, Hongyu Liu, Qiyan Wu, Lingxiong Wang, Yanju Yu, Fan Yin, Cong Feng, Xuewen Ren, Tianyi Liu, Ling Chen and Haiyan Zhu
    Citation: BMC Cancer 2023 23:596
    Content type: Research Published on:

  49. The detailed molecular mechanism between type 2 diabetes mellitus (T2DM) and colorectal cancer (CRC) is still uncertain. Bone morphogenetic protein 4 (BMP4) dysregulation is implicated in T2DM and CRC, respect...

    Authors: Bingwei Ma, Xingchun Wang, Hui Ren, Yingying Li, Haijiao Zhang, Muqing Yang and Jiyu Li
    Citation: BMC Cancer 2023 23:594
    Content type: Research Published on:

  50. The lack of effective and accurate predictive indicators remains a major bottleneck for the improvement of the prognosis of patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Hepatit...

    Authors: Ming-Da Wang, Hao Xiang, Tian-Yu Hong, Abudurexiti Mierxiati, Fei-Hu Yan, Ling Zhang and Chao Wang
    Citation: BMC Cancer 2023 23:593
    Content type: Research Published on:

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